Health Benefits Of Pleurotus Pulmonarius Phoenix Oyster Mushroom 

Pleurotus pulmonarius is commonly known and recognized as a mushroom of medicinal value. Their names are Pleurotus pulmonarius (Fr.) Quell. Also known as Indian oyster, Italian oyster, Phoenix mushroom, and lung oyster. These names are used interchangeably within the article. Production of Pleurotus pulmonarius is increasing worldwide due to its ease of cultivation, high yield, and high nutrition. 

Aqueous extract of Pleurotus pulmonarius contains vitamins B1, B2, C, and calcium. It’s also low in calories. It is low in cholesterol and high in protein, making it highly nutritious. Pleurotus pulmonarius extract has also been found to have anti-inflammatory, anti-cancer, anti-diabetic, anti-hypertensive and antioxidant properties. Bioactive molecules derived from edible mushrooms represent a potential therapeutic option considering their low toxicity and side effects.

Liver Cancer:

Natural bioactive compounds derived from mushrooms and their use in conventional chemotherapy are a growing area of ​​cancer treatment. Polysaccharide-protein complexes were isolated from lung pleurotus using hot water extraction and the effects on cancerous hepatocytes were observed. The results showed that exposing liver cancer cells to lung pleurotus could not only significantly reduce the proliferation of cancer cells both in vitro and infiltration, but also the drug sensitivity of the cells to the chemotherapeutic drug cisplatin. There may also be improvement . In a mouse model, oral administration (200 mg/kg) inhibited cancer cell proliferation. 

Leukaemia:

Worldwide, leukaemia is one of the leading causes of cancer-related deaths and is a cancer of the blood or bone marrow. Using a leukaemia-induced mouse model, metabolites from extracts of Pleurotus pulmonarius have been shown to increase haemoglobin concentration and red blood cell count, helping to combat leukaemia-associated anaemia. Are important. There is a symptom. Leukemia also causes leukocytosis (increased white blood cells), but in these mice, administration of pulmonary leukocyte metabolites before, during, and after exposure to leukemogenic agents prevented or reversed leukocytosis. They also reported immunomodulatory effects of lung pleurotus through its ability to increase total white blood cell counts (including cancer). The highest number, 80 mg/mL, was seen when the highest dose was given.

Colon cancer:

Extracts of Pleurotus pulmonarius from mycelia or fruiting bodies grown in liquid culture were applied to several colon cancer cell lines in vitro. Studies have shown that both types of extracts may contribute to the observed antiproliferative effects (growth). This effect was confirmed in colon cancer cells, which express high levels of galectin-3, thereby reducing their ability to adhere to other cells. This is important for cancer cell progression and metastasis. 

Antihypertensive:

Hypertension is also called hypertension. It is said to be the main cause of death. Angiotensin-converting enzyme (ACE) is a naturally occurring molecule that causes arteries to constrict. The pharmaceutical industry has developed drugs that inhibit ACE and are used to treat high blood pressure. Pleurotus pulmonarius mycelium protein extract has been studied in vitro for use as an ACE inhibitor. Using Pleurotus pulmonarius mycelial water extract, three proteins with ACE inhibitory effects were identified. This provides a platform for further research and therapeutic development using Phoenix mushroom extract and its biologically active components for the treatment of hypertension. 

Antioxidants:

Daily processes in the human body produce free radicals or reactive oxygen species (ROS) that can oxidise biological molecules such as lipids, proteins, and DNA. They play an important role in the progression of the disease. Natural antioxidants are important to correct these effects, and methanolic extracts of the fruiting bodies of Pleurotus pulmonarius have been shown to have antioxidant properties. The ability of Lung Pleurotus to fight free radicals and lipid peroxidation increased in a dose-dependent manner. The optimal concentration was 2mg/ml. Pleurotus pulmonarius had the most potent antioxidant activity for scavenging ROS (hydrogen peroxide).

Antidiabetic:

In vitro, protein extracts of Pleurotus pulmonarius have been shown to have antidiabetic properties. The assay used in this study monitored enzymes in the presence of protein extracts from Pleurotus pulmonarius. Enzymes are involved in carbohydrate metabolism, and research provides good evidence for Pleurotus pulmonarius protein extracts as a way to inhibit these enzymes. A diabetic mouse model (alloxan treatment) was used to investigate the effect of Pleurotus pulmonarius aqueous extract, and the results showed a strong antihyperglycemic effect. These studies show that consuming phoenix mushrooms can significantly lower postprandial blood sugar levels. Therefore, its properties and potential use in controlling blood sugar levels should be taken into account, especially in his type II diabetes. 

Anti-rhinitis:

Allergic rhinitis is the most common atopic disease, and atopy refers to a genetic predisposition to allergies. Allergic rhinitis is characterised by sneezing, itching, nasal congestion, and rhinorrhea. A single dose of 500 mg/kg of Lung Pleurotus had no significant effect on antigen-induced nose rubbing or sneezing in mice, but at 500 mg/kg he observed suppression after 2 weeks of treatment. It was done. Furthermore, a significant suppression of symptoms was observed 4 weeks after rats were given a dose of 200 mg/kg. This indicates that repeated administration of Pleurotus pulmonarius is suitable for treating symptoms associated with allergic rhinitis in this mouse model. 

Antiviral:

Acquired immunodeficiency syndrome (AIDS) is caused by the human immunodeficiency virus (HIV). The HIV (HIV-1 RT) inhibition rate of Pleurotus pulmonarius extract was tested at a concentration level of 1 mg/mL and showed an HIV-1 RT inhibition of 70.8%. This provides excellent in vitro evidence for the potential antiviral properties of Pleurotus pulmonarius.

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