New Delhi: Gat’s microbiome plays an important role With the onset of multiple sclerosis (MS) – an autoimmune disease that affects the central nervous system, finds a study that can provide answers to why Some people have the condition.

The microbiome in the gut is made up of trillions of bacteria and other microorganisms that live in our digestive tract, and are connected to human health and disease. Researchers from Yale University in the US have identified gut bacteria with significant varying degrees of prosperity in patients with MS.

Compared to healthy individuals, MS patients also have a smaller number of bacteria coated with an antibody known as host immunoglobulin A (IGA). Erin Longbrake, Associate Professor of Neurology and Chief Study Investigator. Longbrake said “theoretical, environmental risk factors can guess people at MS because they are changing gut bugs.”

For the study, published in neuroimmunology of neurology and neuroinflammation, the team includes 43 people who are newly evaluated with MS and have not started any kind of immune therapy to treat the disease. This is compared to 42 healthy controls.

The evaluation of their stool samples showed that the species of the faecalibacterium were less abundant in patients with MS, while monoglobus species were more abundant to those who did not – Ms ms. In 43 people with MS, 19 gave researchers an additional stool sample six months after starting B-cell of therapy — a treatment that destroys immune cells contributing to Autoimmune diseases.

The gut microbiomes of these patients are closer to the microbiomes of healthy control than they have pre-treatment, researchers have found. , “Longbrake says. The findings will help explain why some people develop MS, but not to others.

Reference

https://medicine.yale.edu/news-article/gut-microbiome-changes-linked-to-multiple-sclerosis-ms-new-study-finds/#:~:text=The%20researchers%20found%20that%20patients,been%20identified%20in%20prior%20research.

https://zeenews.india.com/health/gut-microbiome-linked-to-multiple-sclerosis-onset-yale-study-reveals-key-bacterial-imbalance-2862116